Understanding prostate cancer progression and survival in African American men

Identifying factors associated with prostate cancer progression and survival in African American men: The RESPOND Cohort

NIH-funded research University of Southern California · NIH-11143205

This project aims to understand why prostate cancer affects African American men more severely by looking at many different factors.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-11143205 on NIH RePORTER

What this research studies

African American men face a much higher risk of developing and dying from prostate cancer compared to white men, and we don't fully understand why. This project, called RESPOND, is a nationwide effort to gather information from over 12,500 African American men diagnosed with prostate cancer. We are collecting details on their stress levels, environment, treatments, genetics, and tumor characteristics. By following these men over several years, we hope to learn more about what causes the disease to progress and how it affects survival.

Who could benefit from this research

Good fit: This project focuses on African American men who have been diagnosed with prostate cancer.

Not a fit: Patients who are not African American or who do not have prostate cancer would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to a better understanding of prostate cancer in African American men, potentially improving diagnosis, treatment, and outcomes for this community.

How similar studies have performed: While individual factors have been explored, this comprehensive, nationwide cohort approach to understanding multiple interacting factors in African American men with prostate cancer is a significant and relatively novel effort.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.