Understanding prostate cancer progression and survival in African American men
Official title: Identifying factors associated with prostate cancer progression and survival in African American men: The RESPOND Cohort
Funded at University of Southern California · NIH-10895911 · Data updated 2026-11-12
This study is looking at what affects how prostate cancer progresses and how well African American men with the disease do over time, by exploring things like stress, healthcare access, genetics, and the environment, to help understand why there are differences in outcomes for this group.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | July 23, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,620,203 |
| NIH project number | 1U01CA287036-01A1 |
| Project ID | NIH-10895911 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American men who have been diagnosed with prostate cancer between 2015 and 2020.
✕Less likely to help
Patients who are not African American or who were diagnosed with prostate cancer outside the specified timeframe may not benefit from this research.
What this research studies
This research investigates the factors that contribute to the progression and survival rates of prostate cancer specifically in African American men. It focuses on various elements such as stress, access to healthcare, genetic factors, and the impact of the environment on health outcomes. The study involves a large cohort of over 12,700 African American men diagnosed with prostate cancer, who will be monitored over several years to gather comprehensive data on their health, lifestyle, and cancer outcomes. By analyzing this information, the research aims to uncover the reasons behind the disparities in prostate cancer outcomes for this population.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for prostate cancer in African American men, potentially reducing mortality rates.
How similar studies have gone: Previous research has shown success in understanding health disparities in cancer outcomes, making this approach both relevant and promising.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Haiman, Christopher Alan — University of Southern California
- Study coordinator: Haiman, Christopher Alan
Related research
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Characterizing epigenetic targets in prostate cancer to help AR-driven cancer
A research project at MD Anderson aims to understand how epigenetic factors shape androgen receptor signaling in prostate cancer to find new ways to treat resistant forms of the disease.
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AR and RNA-binding in prostate cancer resistance
A cancer research grant exploring how the androgen receptor’s interaction with RNA may drive treatment resistance in prostate cancer, with potential to guide new therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.