Understanding prostate cancer in African American men

Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Immunity and Stress (RESPOND)

['FUNDING_OTHER'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-10759094

This study is looking into why African American men are more likely to have aggressive prostate cancer, by gathering information on their health, lifestyle, and genetics to better understand the factors that might be causing this difference.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTHERN CALIFORNIA (nih funded)
Locations1 site (Los Angeles, UNITED STATES)
Trial IDNIH-10759094 on ClinicalTrials.gov

What this research studies

This research investigates the reasons behind the higher rates of aggressive prostate cancer in African American men. It aims to explore various factors including genetics, immune responses, and social stressors that may contribute to this disparity. By establishing a large cohort of 10,000 African American men diagnosed with prostate cancer, the study will collect extensive data on their health behaviors, lifestyle, and genetic information. This comprehensive approach will help identify the biological and social influences on prostate cancer aggressiveness.

Who could benefit from this research

Good fit: Ideal candidates for this research are African American men who have recently been diagnosed with prostate cancer.

Not a fit: Patients who are not of African ancestry or those who do not have a diagnosis of prostate cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for prostate cancer specifically tailored to African American men.

How similar studies have performed: Previous research has indicated that social and biological factors significantly impact cancer outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Disease, Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.