Understanding prostate cancer in African American men

Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Immunity and Stress (RESPOND)

NIH-funded research University of Southern California · NIH-10668262

This study is looking into why African American men are more likely to have aggressive prostate cancer, focusing on things like genetics, immune system responses, and social stress, and it involves gathering information from 10,000 men to better understand these factors.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-10668262 on NIH RePORTER

What this research studies

This research investigates the reasons behind the higher rates of aggressive prostate cancer in African American men. It aims to identify the roles of genetic factors, immune responses, and social stressors in the development and progression of the disease. By establishing a large cohort of 10,000 African American men diagnosed with prostate cancer, the study will collect data on various influences such as lifestyle, health behaviors, and genetic predispositions. This comprehensive approach will help uncover the complex interplay of factors contributing to prostate cancer aggressiveness.

Who could benefit from this research

Good fit: Ideal candidates for this research are African American men who have recently been diagnosed with prostate cancer.

Not a fit: Patients who are not of African ancestry or those who do not have a diagnosis of prostate cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and targeted interventions for prostate cancer in African American men.

How similar studies have performed: Previous research has indicated that social and biological factors significantly impact cancer outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.