Understanding progressive lung disease in rheumatoid arthritis
Defining the molecular and radiologic phenotype of progressive RA-ILD
This project aims to find new ways to tell which people with rheumatoid arthritis-related lung disease are most likely to get worse, so they can receive more effective and safer treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11134444 on NIH RePORTER |
What this research studies
Many people with rheumatoid arthritis can also develop a serious lung condition called interstitial lung disease (RA-ILD), which can worsen over time. Currently, all RA-ILD is treated similarly, even though the disease can affect people differently. This project hopes to find better ways to identify those at highest risk for their lung disease getting worse. Researchers will look at special imaging scans and specific markers in blood samples to better understand who might benefit from different treatments.
Who could benefit from this research
Good fit: This work is relevant for patients diagnosed with rheumatoid arthritis-associated interstitial lung disease (RA-ILD).
Not a fit: Patients without rheumatoid arthritis or interstitial lung disease would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to earlier and more personalized treatments for people with RA-ILD, potentially slowing down lung damage and improving quality of life.
How similar studies have performed: While the overall approach of using biomarkers and imaging is established, this specific combination and focus on progressive RA-ILD represents a novel and untested strategy.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Lee, Joyce Sujin — University of Colorado Denver
- Study coordinator: Lee, Joyce Sujin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.