Understanding pregnancy complications and heart disease risk

PRegnancy OuTcomEs and subclinical Cardiovascular disease sTudy: (PROTECT)

NIH-funded research Northwestern University at Chicago · NIH-10988241

This study is looking at how problems during pregnancy, like high blood pressure and early delivery, might affect heart health later on, and it’s for women who want to understand their risk of heart issues after experiencing these complications.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10988241 on NIH RePORTER

What this research studies

This research investigates the connections between adverse pregnancy outcomes, such as hypertensive disorders and preterm delivery, and the risk of developing subclinical cardiovascular disease later in life. By examining the underlying mechanisms and risk factors, the study aims to identify how these pregnancy complications may indicate future heart health issues. Participants will be monitored over time to assess their cardiovascular health and the impact of their pregnancy experiences. This approach seeks to provide insights into preventive measures for women at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have experienced adverse pregnancy outcomes, such as hypertensive disorders or preterm delivery.

Not a fit: Patients who have not experienced any adverse pregnancy outcomes may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved screening and preventive strategies for women at risk of cardiovascular disease following adverse pregnancy outcomes.

How similar studies have performed: Previous research has shown promising results in understanding the links between pregnancy complications and cardiovascular health, indicating that this approach is grounded in established findings.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.