Understanding Pregnancy Anxiety and Baby's Allergy Risk
Antenatal Anxiety and Dyadic Immune Risk(ADIR Study)
This project looks at how anxiety during pregnancy might affect a baby's immune system and their chances of developing allergies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11109573 on NIH RePORTER |
What this research studies
We are following 200 mothers and their babies from the second trimester of pregnancy until the babies are one year old. We want to see if mothers who experience anxiety during pregnancy show different immune responses compared to those who don't. We will also check the babies' immune systems at birth to understand if there's a connection between a mother's anxiety, a baby's early immune activity, and their risk for allergies later on. This helps us understand how early life experiences might shape a child's health.
Who could benefit from this research
Good fit: Pregnant women in their second trimester, both those experiencing clinically significant anxiety and healthy controls, along with their babies, are ideal candidates for this observational study.
Not a fit: Patients not pregnant or whose children are older than 12 months would not directly benefit from participating in this specific observational timeline.
Why it matters
Potential benefit: If successful, this work could help us understand how to identify babies at higher risk for allergies and potentially develop ways to prevent them.
How similar studies have performed: While maternal anxiety and immune dysregulation have been linked to allergy risk separately, this study is novel in attempting to connect dyadic maternal and neonatal immune changes to allergy risk in the same mother-child pairs.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Osborne, Lauren M — Weill Medical Coll of Cornell Univ
- Study coordinator: Osborne, Lauren M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.