Understanding pouch-related disorders after surgery for ulcerative colitis
Treatment Approaches and Outcomes in Pouch-related Disorders after Colectomy for Ulcerative Colitis
['FUNDING_OTHER'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10990528
This study is looking to better understand pouchitis and other related issues that can happen after a specific surgery for people with certain bowel conditions, so we can find better ways to treat and care for patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-10990528 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the understanding of pouchitis and other inflammatory conditions that can occur after a specific type of surgery called restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA). The principal investigator, Dr. Edward Barnes, aims to develop new skills in comparative effectiveness research and precision medicine, utilizing real-world data and machine learning techniques. By collaborating with a mentorship committee of experts, the research will explore patient-reported outcomes and risk modeling to enhance care for patients undergoing this surgery. The goal is to provide better treatment approaches and outcomes for individuals affected by these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have undergone restorative proctocolectomy with ileal pouch-anal anastomosis and are experiencing pouchitis or related inflammatory conditions.
Not a fit: Patients who have not undergone restorative proctocolectomy or do not have pouch-related disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better management of pouch-related disorders for patients.
How similar studies have performed: Previous research in similar areas has shown promise in improving outcomes for patients with inflammatory bowel diseases, indicating that this approach could be beneficial.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BARNES, EDWARD — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: BARNES, EDWARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.