Understanding Post-COVID Syndrome and Its Types
Temporal Phenotypes and Risk Models for the Post-COVID Syndrome and its sub-types
This project looks at electronic health records to understand the different ways Long COVID affects people over time and who might be at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11129801 on NIH RePORTER |
What this research studies
Many people experience lingering health issues after a COVID-19 infection, often called Long COVID or PASC. This project uses health information from seven hospital systems across the U.S. to learn more about these long-lasting symptoms. We want to identify different patterns of symptoms that appear over time and understand what causes them. The goal is to create models that can help predict which patients might develop Long COVID and how their condition might change.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced COVID-19 infection and are now dealing with persistent symptoms, often referred to as Long COVID or PASC.
Not a fit: Patients who have not had COVID-19 or are not experiencing lingering symptoms after their acute infection would not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could help doctors better identify, understand, and eventually treat patients suffering from Long COVID by predicting who is at risk and how their symptoms might evolve.
How similar studies have performed: While the understanding of Long COVID is still developing, this approach of using large-scale electronic health records to identify symptom patterns has shown promise in other complex conditions.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Estiri, Hossein — Massachusetts General Hospital
- Study coordinator: Estiri, Hossein
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.