NIH-funded research R01 grant

Understanding positive emotions in young adults with bipolar disorder

Official title: Positive Emotion in Bipolar Disorder Onset and Illness Course in Emerging Adults

Funded at University of Colorado · NIH-10994670 · Data updated 2026-11-12

This study is looking at how difficulties with managing positive emotions might influence the start and development of bipolar disorder in young adults, and it’s for people who are at high risk, recently diagnosed, or at low risk for the condition.

More Bipolar Disorder research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado
NIH-funded
Lab location1 site (Boulder, UNITED STATES)
Project startDecember 5, 2023
Project endNovember 30, 2028
Funding year2025
Award (this year)$638,466
NIH project number5R01MH131803-02
Project IDNIH-10994670 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include emerging adults who are either diagnosed with bipolar disorder, at high risk for developing it, or at low risk.

Less likely to help

Patients who are not within the emerging adult age range or who do not have a history of mood disorders may not benefit from this research.

What this research studies

This research investigates how positive emotion dysregulation (PED) affects the onset and progression of bipolar disorder (BD) in emerging adults. By using a combination of behavioral assessments and neuroimaging techniques, the study aims to identify patterns of PED in individuals at high risk for BD, those who have recently been diagnosed, and those at low risk. Over a two-year period, participants will be monitored to see how their emotional responses relate to the development and course of bipolar symptoms. The goal is to better understand the role of positive emotions in the early stages of bipolar disorder.

Why it matters

Potential benefit: If successful, this research could lead to improved early detection and intervention strategies for bipolar disorder in young adults.

How similar studies have gone: Previous research has shown promising results in understanding emotional dysregulation in bipolar disorder, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Colorado
    Boulder, United States
    Active

Researchers

  • Principal investigator: Gruber, June L — University of Colorado
  • Study coordinator: Gruber, June L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.