Understanding placental problems in common pregnancy issues
Official title: Enhancing insight into placental dysfunction in common obstetric disorders using placental multiomics
Funded at Institute for Systems Biology · NIH-10889514 · Data updated 2026-11-12
This study is looking at how problems with the placenta can lead to issues like high blood pressure during pregnancy, early births, and babies not growing enough, and it hopes to find new ways to help moms and babies stay healthy.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Institute for Systems Biology NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | July 11, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $293,756 |
| NIH project number | 1R21HD112819-01A1 |
| Project ID | NIH-10889514 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant individuals experiencing complications such as preeclampsia, fetal growth restriction, or preterm birth.
✕Less likely to help
Patients with uncomplicated pregnancies or those not experiencing any obstetric disorders may not benefit from this research.
What this research studies
This research investigates how placental dysfunction contributes to common obstetric disorders such as preeclampsia, preterm birth, and fetal growth restriction. By using advanced multiomic analysis, the study aims to uncover the molecular mechanisms behind these conditions, which are often complex and interrelated. The research utilizes a large dataset of placental samples from various pregnancy outcomes to identify patterns that could lead to better understanding and treatment of these disorders. Patients may benefit from insights that could improve maternal and fetal health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for pregnant individuals facing complications.
How similar studies have gone: Previous research has shown promise in using multiomic approaches to understand complex biological systems, suggesting potential for success in this area.
Where this research is happening
-
Institute for Systems Biology
Seattle, United States Active
Researchers
- Principal investigator: Hadlock, Jennifer — Institute for Systems Biology
- Study coordinator: Hadlock, Jennifer
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.