Understanding placental problems in common pregnancy issues
Enhancing insight into placental dysfunction in common obstetric disorders using placental multiomics
['FUNDING_R21'] · INSTITUTE FOR SYSTEMS BIOLOGY · NIH-10889514
This study is looking at how problems with the placenta can lead to issues like high blood pressure during pregnancy, early births, and babies not growing enough, and it hopes to find new ways to help moms and babies stay healthy.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INSTITUTE FOR SYSTEMS BIOLOGY (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10889514 on ClinicalTrials.gov |
What this research studies
This research investigates how placental dysfunction contributes to common obstetric disorders such as preeclampsia, preterm birth, and fetal growth restriction. By using advanced multiomic analysis, the study aims to uncover the molecular mechanisms behind these conditions, which are often complex and interrelated. The research utilizes a large dataset of placental samples from various pregnancy outcomes to identify patterns that could lead to better understanding and treatment of these disorders. Patients may benefit from insights that could improve maternal and fetal health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals experiencing complications such as preeclampsia, fetal growth restriction, or preterm birth.
Not a fit: Patients with uncomplicated pregnancies or those not experiencing any obstetric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for pregnant individuals facing complications.
How similar studies have performed: Previous research has shown promise in using multiomic approaches to understand complex biological systems, suggesting potential for success in this area.
Where this research is happening
SEATTLE, UNITED STATES
- INSTITUTE FOR SYSTEMS BIOLOGY — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HADLOCK, JENNIFER — INSTITUTE FOR SYSTEMS BIOLOGY
- Study coordinator: HADLOCK, JENNIFER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.