NIH-funded research NIH-funded research

Understanding persistent bloodstream infections

Official title: Administrative Core

Funded at Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · NIH-11091663 · Data updated 2026-11-12

This study is looking at how our bodies and harmful germs interact when someone has a serious bloodstream infection that doesn't get better with regular treatments, and it's designed to help doctors find better ways to help patients recover.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
NIH-funded
Lab location1 site (Torrance, United States)
Project startAugust 10, 2023
Project endMay 31, 2028
Funding year2025
Award (this year)$179,100
NIH project number5U19AI172713-03
Project IDNIH-11091663 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing life-threatening bloodstream infections that have not cleared with appropriate therapy.

Less likely to help

Patients with bloodstream infections that respond well to standard treatments may not benefit from this research.

What this research studies

This research investigates the complex interactions between the host and pathogens that lead to severe bloodstream infections that do not respond to standard treatments. By employing a systems-biology approach, the project aims to integrate various expertise and technologies to enhance understanding and management of these infections. The Administrative Network Core will facilitate collaboration among researchers and ensure efficient coordination of resources and activities, ultimately aiming to improve patient outcomes.

Why it matters

Potential benefit: If successful, this research could lead to better treatment strategies for patients suffering from persistent bloodstream infections.

How similar studies have gone: Other research has shown promise in understanding host-pathogen interactions using systems-biology approaches, indicating potential for success in this area.

Where this research is happening

  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
    Torrance, United States
    Active

Researchers

  • Principal investigator: Yeaman, Michael R — Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
  • Study coordinator: Yeaman, Michael R

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Other NIH-funded projects on the same topics.

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  • New CPET approach to tell apart heart problems from muscle weakness

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    NIH research Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, United States · NIH-11411311

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.