Understanding patient priorities for quality of life in lung transplant decisions
Official title: Patient Priorities in Lung Transplant: Quality of Life Outcomes to Inform Decision Making
Funded at Temple Univ of the Commonwealth · NIH-11014341 · Data updated 2026-11-12
This study is looking at how people with severe lung disease and their caregivers think about what matters most to them when deciding whether to get a lung transplant, so they can create a helpful tool that makes it easier for them to understand how the transplant might affect their quality of life.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $146,847 |
| NIH project number | 5K01HL161330-03 |
| Project ID | NIH-11014341 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients with end-stage lung disease and their caregivers who are contemplating lung transplantation.
✕Less likely to help
Patients who are not considering lung transplantation or who have already undergone the procedure may not benefit from this research.
What this research studies
This research investigates how patients with end-stage lung disease and their caregivers prioritize quality of life outcomes when making decisions about lung transplantation. By engaging patients and caregivers through interviews and surveys, the study aims to identify key factors that influence their decision-making process. The findings will help develop a decision aid that effectively communicates the potential impacts of transplantation on quality of life, ultimately supporting patients in making informed choices about their care.
Why it matters
Potential benefit: If successful, this research could lead to improved decision-making tools that enhance the quality of life for patients considering lung transplantation.
How similar studies have gone: Previous research has shown that decision aids can significantly improve patient understanding and satisfaction in complex medical decisions, indicating a promising approach for this study.
Where this research is happening
-
Temple Univ of the Commonwealth
Philadelphia, United States Active
Researchers
- Principal investigator: Hollin, Ilene L. — Temple Univ of the Commonwealth
- Study coordinator: Hollin, Ilene L.
Related research
Other NIH-funded projects on the same topics.
-
Exercise-based frailty program for people awaiting lung transplants
A tailored exercise and lifestyle program is being tested to reduce frailty and improve outcomes for people waiting for a lung transplant.
-
Understanding why a lung transplant sometimes fails early and how to tailor treatment
A study of people receiving lung transplants to find molecular differences that cause early graft failure and point to better, personalized therapies.
-
Targeting inflammation and alloimmunity in lung transplant recipients with clazakizumab
A study to see if blocking IL-6 with clazakizumab can improve survival and reduce rejection in people who have received a lung transplant.
-
Vaccination responses in lung transplant patients
This grant studies how people who have received lung transplants respond to COVID-19 vaccines and why their antibody responses may be limited.
-
The Post-Lung Transplant Aging in Immune Cells in Donor Lungs
This grant explores how aging donor lungs affect lung transplant outcomes by studying immune cells called alveolar macrophages.
-
Predictors of Lung Transplant Success and Costs
This study looks at what pre-transplant patient factors and biology predict a smooth recovery and lower costs after lung transplant.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.