Understanding Pancreatitis and New Treatment Paths
Elucidating novel mechanisms for pancreatitis through calcineurin signaling
This project explores how a specific cell process contributes to acute pancreatitis, hoping to find new ways to treat this painful condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11143227 on NIH RePORTER |
What this research studies
Acute pancreatitis is a very painful and serious health issue with limited treatment options. Our goal is to find new, targeted treatments to lessen the severity of this disease. We've found that a protein called calcineurin plays a big role in how pancreatitis affects pancreatic cells. This project aims to understand the exact steps calcineurin takes to cause problems and identify specific targets within these steps that could be blocked by new medicines.
Who could benefit from this research
Good fit: Patients with acute pancreatitis could potentially benefit from future treatments developed from this fundamental understanding of the disease.
Not a fit: Patients without acute pancreatitis would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new, more effective treatments for acute pancreatitis, reducing pain and improving patient outcomes.
How similar studies have performed: This project builds on the researchers' own prior discoveries and compelling preliminary data, suggesting a strong foundation for this novel approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Husain, Sohail Z — Stanford University
- Study coordinator: Husain, Sohail Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.