Understanding pain severity in sickle cell disease
Predictors of Pain Severity and Pain-Related Outcomes in Individuals with Sickle Cell Disease
This study is looking at what might cause different levels of pain in people with sickle cell disease, so doctors can better help those who are at risk for severe pain and find new ways to manage it without using opioids.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10904941 on NIH RePORTER |
What this research studies
This research investigates the factors that predict pain severity and related outcomes in individuals with sickle cell disease (SCD). By using a prospective, longitudinal study design, the research aims to identify psychological and sensory predictors of pain outcomes. The study will help clinicians better understand which patients are at risk for severe pain, thereby improving management strategies and informing clinical trials for non-opioid pain interventions. The findings could lead to more personalized care for patients suffering from SCD-related pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with sickle cell disease, particularly those experiencing varying levels of pain.
Not a fit: Patients without a diagnosis of sickle cell disease or those who do not experience pain related to the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies and better quality of life for patients with sickle cell disease.
How similar studies have performed: Previous research has shown promise in identifying psychological and sensory factors as predictors of pain outcomes in chronic pain conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kenney, Martha Obeng — Duke University
- Study coordinator: Kenney, Martha Obeng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.