Understanding pain processing in adolescents with multiple pain conditions
Official title: Disrupted Spatial and Temporal Nociceptive Filtering in Adolescents with and Risk for Overlapping Pain Conditions
Funded at Cincinnati Childrens Hosp Med Ctr · NIH-10906365 · Data updated 2026-11-12
This study is looking at how teenagers with ongoing pain feel and process their pain differently than those with just one area of pain or those who are healthy, to help find better ways to treat their pain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $567,174 |
| NIH project number | 5R01NS126289-02 |
| Project ID | NIH-10906365 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adolescents aged 21 and under who experience chronic overlapping pain conditions.
✕Less likely to help
Patients who do not experience pain or have localized pain conditions without overlap may not benefit from this research.
What this research studies
This research investigates how adolescents with chronic overlapping pain conditions (COPCs) process pain differently compared to those with localized pain or healthy individuals. By using advanced sensory testing methods, the study aims to identify disruptions in how the brain filters pain signals over space and time. This could help in understanding the underlying mechanisms of pain in youth and potentially lead to better treatment strategies. The research will involve comparing pain responses among different groups of adolescents to uncover these differences.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for adolescents suffering from chronic pain conditions.
How similar studies have gone: Previous studies have shown promising results in understanding pain processing, but this specific approach to COPCs is novel and largely untested.
Where this research is happening
-
Cincinnati Childrens Hosp Med Ctr
Cincinnati, United States Active
Researchers
- Principal investigator: King, Christopher D — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: King, Christopher D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.