Understanding pain processing in adolescents with multiple pain conditions

Disrupted Spatial and Temporal Nociceptive Filtering in Adolescents with and Risk for Overlapping Pain Conditions

NIH-funded research Cincinnati Childrens Hosp Med Ctr · NIH-10906365

This study is looking at how teenagers with ongoing pain feel and process their pain differently than those with just one area of pain or those who are healthy, to help find better ways to treat their pain.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-10906365 on NIH RePORTER

What this research studies

This research investigates how adolescents with chronic overlapping pain conditions (COPCs) process pain differently compared to those with localized pain or healthy individuals. By using advanced sensory testing methods, the study aims to identify disruptions in how the brain filters pain signals over space and time. This could help in understanding the underlying mechanisms of pain in youth and potentially lead to better treatment strategies. The research will involve comparing pain responses among different groups of adolescents to uncover these differences.

Who could benefit from this research

Good fit: Ideal candidates for this research include adolescents aged 21 and under who experience chronic overlapping pain conditions.

Not a fit: Patients who do not experience pain or have localized pain conditions without overlap may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for adolescents suffering from chronic pain conditions.

How similar studies have performed: Previous studies have shown promising results in understanding pain processing, but this specific approach to COPCs is novel and largely untested.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.