Understanding Pain in Chronic Pancreatitis with P-QST
P-QST Project: Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
This research aims to find a better way to predict which patients with chronic pancreatitis will get relief from their pain after treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11126630 on NIH RePORTER |
What this research studies
Many people with chronic pancreatitis experience severe abdominal pain, which greatly impacts their daily lives. While treatments like surgery or endotherapy are available, it's hard to know beforehand if they will truly help with the pain. This is because pain can be complex, sometimes involving how the brain processes pain signals. Our goal is to use a special method called Pancreatic Quantitative Sensory Testing (P-QST) to understand different types of pain in patients and use this information to predict who will benefit most from specific treatments.
Who could benefit from this research
Good fit: Ideal candidates for this type of research would be patients experiencing abdominal pain due to chronic pancreatitis who are considering or undergoing invasive treatments.
Not a fit: Patients whose pain is not related to chronic pancreatitis or who are not seeking invasive treatments for their pain may not directly benefit from this specific approach.
Why it matters
Potential benefit: If successful, this work could help doctors choose the most effective pain treatments for individuals with chronic pancreatitis, reducing unnecessary procedures and improving quality of life.
How similar studies have performed: Preliminary data suggests that P-QST can categorize patients with chronic pancreatitis into different pain groups, indicating a promising foundation for this predictive approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Phillips, Anna Evans — University of Pittsburgh at Pittsburgh
- Study coordinator: Phillips, Anna Evans
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.