Understanding pain in autistic adults

Measurement and Mechanisms of Pain in Autistic Adults

NIH-funded research Ohio State University · NIH-11098599

This project looks at how autistic adults feel and express pain so care can better recognize and treat it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-11098599 on NIH RePORTER

What this research studies

If you are an autistic adult, researchers will compare how you experience and show pain with non-autistic adults. They will use questionnaires, controlled sensory and pain tasks, and measures of anxiety and nervous system or brain responses to gather information. The team aims to identify whether sensory sensitivity, pain-related anxiety, or changes in nervous system processing contribute to persistent pain. Results will be used to guide clearer ways for clinicians to spot and manage pain in autistic adults.

Who could benefit from this research

Good fit: Autistic adults (21 years and older) who can give informed consent and take part in sensory and pain testing are the ideal candidates.

Not a fit: Children, people without an autism diagnosis, or people who cannot tolerate or consent to experimental pain or sensory testing are unlikely to benefit from participating.

Why it matters

Potential benefit: If successful, this work could lead to better pain detection and more appropriate pain treatments for autistic adults.

How similar studies have performed: Smaller prior studies have found altered pain sensitivity, increased pain-related anxiety, and different brain responses in autistic people, but comprehensive work in adults is still emerging.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.