Understanding pain from trigeminal nerve injuries
Mechanisms of Pain Associated with Trigeminal Nerve Injury
This study is looking at how a common anti-seizure medication called carbamazepine can help relieve pain from injuries to the trigeminal nerve, which affects feeling in the face, and it aims to find better treatments for people dealing with this kind of pain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10892194 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind pain caused by injuries to the trigeminal nerve, which is responsible for sensation in the face. The study focuses on how the anti-seizure medication carbamazepine affects pain relief specifically for trigeminal nerve injuries compared to other types of nerve injuries. By using animal models, researchers aim to identify the differences in nerve responses to injury and how these differences can lead to more effective treatments for patients suffering from trigeminal nerve pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic pain due to trigeminal nerve injuries.
Not a fit: Patients with pain from other types of nerve injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for patients with trigeminal nerve injuries.
How similar studies have performed: Previous research has shown that targeting specific nerve responses can lead to effective pain relief, indicating potential success for this approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Gold, Michael S — University of Pittsburgh at Pittsburgh
- Study coordinator: Gold, Michael S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.