Understanding Pain and Nutrition in Alzheimer's Disease

Pain and Nutrition in Dementia and Alzheimer's-2 (PANDA-2)

NIH-funded research University of Florida · NIH-11167883

This project explores how diet and pain might be connected in older adults with Alzheimer's disease and related dementias.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11167883 on NIH RePORTER

What this research studies

Many older adults experience both chronic pain and Alzheimer's disease, and we believe these conditions might share common causes. This project looks at how our genes are influenced by factors like diet, which could affect both pain and Alzheimer's. We want to understand if specific nutrients, like Vitamins A and D, play a role in these connections. By learning more about these links, we hope to find new ways to help manage pain and potentially slow the progression of Alzheimer's.

Who could benefit from this research

Good fit: This research is relevant for older adults living with chronic pain and Alzheimer's disease or related dementias.

Not a fit: Patients without Alzheimer's disease or chronic pain may not directly benefit from this specific line of research.

Why it matters

Potential benefit: If successful, this work could lead to new dietary recommendations or treatments to help manage chronic pain and potentially impact the progression of Alzheimer's disease.

How similar studies have performed: While the connection between diet, epigenetics, pain, and Alzheimer's is a newer area, previous work has suggested that chronic pain can predict Alzheimer's development and that epigenetics influences both conditions.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.