Understanding outcomes and treatment preferences for heart infections related to drug use
Official title: Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferences
Funded at Univ of North Carolina Chapel Hill · NIH-10810845 · Data updated 2026-11-12
This study is looking at what happens to people in North Carolina after they leave the hospital for a serious heart infection caused by drug use, focusing on their experiences, challenges like overdoses or returning to the hospital, and what kind of treatment they prefer to help them with their ongoing struggles.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | April 1, 2020 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $176,065 |
| NIH project number | 5K23DA049946-05 |
| Project ID | NIH-10810845 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have been hospitalized for drug-use associated infective endocarditis and are dealing with drug use disorders.
✕Less likely to help
Patients who have not experienced drug use or do not have a history of infective endocarditis may not benefit from this research.
What this research studies
This research investigates the post-hospitalization experiences of patients who have been treated for drug-use associated infective endocarditis (DUA-IE), a serious heart infection linked to injecting drugs. The study aims to identify the incidence of negative outcomes such as drug overdose and hospital readmission after discharge, while also exploring patients' perspectives on their treatment preferences. By focusing on patients in North Carolina, the research seeks to understand how to better address ongoing drug use disorders that contribute to DUA-IE and improve overall care for these individuals.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and support systems for patients recovering from drug-use associated heart infections.
How similar studies have gone: While there has been research on infective endocarditis, this specific focus on drug use-associated cases and their post-hospitalization outcomes is relatively novel.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Schranz, Asher Jacob — Univ of North Carolina Chapel Hill
- Study coordinator: Schranz, Asher Jacob
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.