Understanding outcomes and treatment preferences for heart infections related to drug use

Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferences

['FUNDING_OTHER'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10810845

This study is looking at what happens to people in North Carolina after they leave the hospital for a serious heart infection caused by drug use, focusing on their experiences, challenges like overdoses or returning to the hospital, and what kind of treatment they prefer to help them with their ongoing struggles.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIV OF NORTH CAROLINA CHAPEL HILL (nih funded)
Locations1 site (CHAPEL HILL, UNITED STATES)
Trial IDNIH-10810845 on ClinicalTrials.gov

What this research studies

This research investigates the post-hospitalization experiences of patients who have been treated for drug-use associated infective endocarditis (DUA-IE), a serious heart infection linked to injecting drugs. The study aims to identify the incidence of negative outcomes such as drug overdose and hospital readmission after discharge, while also exploring patients' perspectives on their treatment preferences. By focusing on patients in North Carolina, the research seeks to understand how to better address ongoing drug use disorders that contribute to DUA-IE and improve overall care for these individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been hospitalized for drug-use associated infective endocarditis and are dealing with drug use disorders.

Not a fit: Patients who have not experienced drug use or do not have a history of infective endocarditis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and support systems for patients recovering from drug-use associated heart infections.

How similar studies have performed: While there has been research on infective endocarditis, this specific focus on drug use-associated cases and their post-hospitalization outcomes is relatively novel.

Where this research is happening

CHAPEL HILL, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Infectious Disease Pathway, Infectious Diseases, Infectious Disorder, Communicable Diseases, Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.