Understanding Osteoporosis Risk from Genes and Gut Health
Administrative Core
This project aims to understand how our genes and gut bacteria contribute to osteoporosis risk in men and women from different backgrounds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-11118816 on NIH RePORTER |
What this research studies
We are exploring how your DNA (genome) and the genetic material of your gut bacteria (metagenome) influence bone-building and bone-breaking cells at a very detailed level. This includes looking at both males and females, as well as major ethnic groups, to get a complete picture of osteoporosis risk. By combining information from many different biological sources, we hope to uncover new ways to predict and prevent bone weakening. This administrative core helps coordinate all these complex efforts to ensure the overall project runs smoothly and effectively.
Who could benefit from this research
Good fit: This research is relevant to individuals concerned about osteoporosis, particularly men and women from diverse ethnic backgrounds.
Not a fit: Patients not at risk for or currently experiencing osteoporosis may not directly benefit from this specific research focus.
Why it matters
Potential benefit: If successful, this work could lead to new ways to identify individuals at high risk for osteoporosis and develop personalized strategies for prevention and treatment.
How similar studies have performed: This project proposes a novel and comprehensive approach to integrate genetic and gut microbiome data for osteoporosis risk, building on existing knowledge in each area.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Deng, Hong-Wen — Tulane University of Louisiana
- Study coordinator: Deng, Hong-Wen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.