Understanding osteoarthritis and its impact on pain and function
Novel Insights into Osteoarthritis, Pain and Function: MOST4
This study is looking at how osteoarthritis affects people and what factors influence their pain and ability to move, and it's inviting individuals, especially from underrepresented groups, to help us learn more so we can create better treatments for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11056738 on NIH RePORTER |
What this research studies
This research investigates the progression of osteoarthritis (OA) and the factors influencing pain and function in affected individuals. It involves recruiting participants, including those from underrepresented minority groups, to gather comprehensive data on pain, biomechanics, and joint health through various methods, including MRI imaging. The study aims to enhance our understanding of OA and develop targeted treatment strategies that could improve patient outcomes. Participants will contribute to a large dataset that informs future research and treatment approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with knee osteoarthritis or those at risk of developing it, particularly from underrepresented minority groups.
Not a fit: Patients with advanced osteoarthritis who are not eligible for the study or those with unrelated conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, more effective treatments for osteoarthritis that improve pain management and functional outcomes for patients.
How similar studies have performed: Previous iterations of the MOST study have successfully contributed to our understanding of osteoarthritis, indicating that this approach has a strong foundation and potential for further advancements.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Felson, David Tobin — Boston University Medical Campus
- Study coordinator: Felson, David Tobin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.