Understanding Oral Cancer Survival Differences Across Ancestries with AI
Study of Biological and Radiographic Biomarkers and Association with Ancestry and Survival Disparities in Oral Cavity Squamous Cell Carcinoma Using AI Approaches
This project aims to understand why patients with oral cavity squamous cell carcinoma from African ancestry sometimes have worse survival rates than those from European ancestry.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11162368 on NIH RePORTER |
What this research studies
Oral cavity squamous cell carcinoma is a serious cancer, and we know that patients of African ancestry often face poorer outcomes compared to those of European ancestry. We want to uncover the reasons behind these differences, which are not yet well understood. Our team will use advanced artificial intelligence to look closely at existing patient information, including biological samples, imaging scans, and clinical details, from a large group of patients. By comparing these factors between different ancestries, we hope to identify unique characteristics that contribute to these survival disparities.
Who could benefit from this research
Good fit: This research focuses on understanding existing data from patients previously diagnosed with oral cavity squamous cell carcinoma, particularly those of African and European ancestry.
Not a fit: Patients without oral cavity squamous cell carcinoma or those not represented in the analyzed ancestry groups may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of oral cancer disparities, paving the way for more targeted and effective treatments for all patients.
How similar studies have performed: While the specific causes of these disparities are poorly understood, this novel approach aims to fill a significant knowledge gap by using comprehensive, racially diverse clinical data.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Gaykalova, Daria a — University of Maryland Baltimore
- Study coordinator: Gaykalova, Daria a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.