Understanding Opioid Withdrawal and New Treatments
Discriminative Stimulus Effects of Opioid Withdrawal
This work explores how cannabidiol (CBD) and related compounds might help people with opioid use disorder.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11001926 on NIH RePORTER |
What this research studies
Opioid use disorder is a serious public health crisis, with many people affected and overdose deaths rising, especially with fentanyl. While current medications exist, there's a strong need for new, non-opioid treatments that have fewer side effects and less potential for abuse. This research looks into the potential of CBD, a component of cannabis, which has shown promise in early studies for treating various aspects of opioid use disorder. We are also exploring if combining CBD with Δ9-tetrahydrocannabinol (THC) could be even more effective.
Who could benefit from this research
Good fit: This research is relevant for individuals living with opioid use disorder who are seeking new treatment options.
Not a fit: Patients not experiencing opioid use disorder would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new, non-opioid medications for opioid use disorder that are safer and more effective than current options.
How similar studies have performed: Pilot studies, other preclinical work, and a recent human study suggest CBD's promise for treating opioid use disorder.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: France, Charles P — University of Texas Hlth Science Center
- Study coordinator: France, Charles P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.