NIH-funded research NIH-funded research

Understanding non-falciparum malaria and its transmission

Official title: Emergents International Centers of Excellence for Malaria Research

Funded at University of Florida · NIH-11077835 · Data updated 2026-11-12

This study is looking at two types of malaria that are often ignored, to help find better ways to diagnose and understand how they spread, especially in children under 11 in Central Africa, where malaria is a big health concern.

More Malaria research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida
NIH-funded
Lab location1 site (Gainesville, United States)
Project startApril 22, 2024
Project endMarch 31, 2029
Funding year2025
Award (this year)$167,742
NIH project number5U19AI181594-02
Project IDNIH-11077835 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years living in Central Africa who may be infected with non-falciparum malaria.

Less likely to help

Patients outside the age range of 0-11 years or those not residing in Central Africa may not benefit from this research.

What this research studies

This research focuses on non-falciparum malaria, specifically the parasites P. ovale and P. malariae, which are often overlooked in malaria studies. By using advanced genomic techniques, the project aims to accurately diagnose these infections, quantify their presence in the population, and assess how they are transmitted by mosquitoes. The research will also evaluate the resistance of these mosquitoes to insecticides, which is crucial for developing effective control strategies. This work is particularly important for children under 11 years old in Central Africa, where malaria remains a significant health threat.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for non-falciparum malaria, ultimately reducing the disease burden in affected populations.

How similar studies have gone: While research on P. falciparum malaria is extensive, studies focusing on non-falciparum malaria are less common, making this approach relatively novel.

Where this research is happening

  • University of Florida
    Gainesville, United States
    Active

Researchers

  • Principal investigator: Dinglasan, Rhoel David Ramos — University of Florida
  • Study coordinator: Dinglasan, Rhoel David Ramos

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.