Understanding New Take-Home Methadone Rules

Take-home expansion: Scope and impact study (THESIS)

NIH-funded research Friends Research Institute, INC. · NIH-11118963

This research looks at how recent changes to take-home methadone rules are affecting people receiving treatment for opioid use disorder.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFriends Research Institute, INC. NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11118963 on NIH RePORTER

What this research studies

For many years, federal rules made it difficult for patients to get take-home methadone, requiring frequent clinic visits. Recently, these rules changed to allow more flexibility, letting clinics offer more take-home doses to help reduce crowding and make treatment easier to access. This project wants to understand how these new rules are being put into practice at clinics across the country. We also want to see how these changes are impacting patient outcomes and develop ways to predict who can safely receive take-home methadone.

Who could benefit from this research

Good fit: This research focuses on patients who are currently receiving methadone treatment for opioid use disorder.

Not a fit: Patients not receiving methadone or those without opioid use disorder would not directly benefit from this particular research.

Why it matters

Potential benefit: If successful, this work could lead to more flexible and accessible methadone treatment, making it easier for patients to manage their opioid use disorder.

How similar studies have performed: The recent regulatory changes are new, so this research is novel in its approach to understanding their real-world impact on patient care and outcomes.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.