Understanding new sources of schistosomiasis infections in Africa and China
Schistosomiasis at the edge of elimination: characterizing sources of new infections in residual transmission hotspots
This study is looking into how schistosomiasis spreads, especially in areas of sub-Saharan Africa and China, by examining the genetic makeup of the parasite to find out where new infections come from, which will help create better ways to stop this infection from affecting people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10508509 on NIH RePORTER |
What this research studies
This research investigates the ongoing transmission of schistosomiasis, a waterborne infection affecting millions, particularly in hotspots in sub-Saharan Africa and China. By utilizing genomic tools and extensive epidemiological data, the study aims to identify the origins of new infections, which may stem from human hosts, other mammals, or imported cases. The research will analyze genetic information from the Schistosoma japonicum parasite to trace its ancestry and understand how it spreads within communities. This knowledge is crucial for developing effective control strategies to eliminate schistosomiasis.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living in or near schistosomiasis hotspots in sub-Saharan Africa and China.
Not a fit: Patients who do not reside in areas affected by schistosomiasis or who are not at risk of infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for controlling and potentially eliminating schistosomiasis, benefiting millions at risk of infection.
How similar studies have performed: Previous research has shown success in using genomic approaches to understand transmission dynamics of infectious diseases, suggesting this method could yield valuable insights for schistosomiasis as well.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Carlton, Elizabeth — University of Colorado Denver
- Study coordinator: Carlton, Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.