Understanding nerve damage caused by HIV
Pathogenesis of HIV-associated sensory neuropathy
This study is looking into sensory neuropathy, a painful condition that many people with HIV experience, to find out what causes it and how we can create better treatments to help relieve their discomfort.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project ID | NIH-10909241 on NIH RePORTER |
What this research studies
This research investigates sensory neuropathy, a common condition affecting individuals with HIV, which causes significant pain and discomfort. The study aims to uncover the underlying mechanisms of this neuropathy to develop targeted treatments. By examining specific proteins and signaling pathways involved in nerve damage, researchers hope to identify new therapeutic strategies that could provide relief for patients suffering from this condition. The approach includes both laboratory studies and analysis of patient samples to ensure a comprehensive understanding of the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with HIV who are experiencing sensory neuropathy.
Not a fit: Patients without HIV or those who do not have sensory neuropathy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective pain relief therapies specifically for patients with HIV-associated sensory neuropathy.
How similar studies have performed: Previous research has shown promise in understanding neuropathic pain mechanisms, but this specific approach targeting HIV-related sensory neuropathy is relatively novel.
Where this research is happening
Galveston, United States
- University of Texas Med Br Galveston — Galveston, United States (Active)
Researchers
- Principal investigator: Yuan, Subo — University of Texas Med Br Galveston
- Study coordinator: Yuan, Subo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.