Understanding Muscle Structure and Movement

Noninvasive tools for assessing muscle structure and function

NIH-funded research Northwestern University · NIH-11135329

This project aims to develop a new way to measure muscle strength and stiffness without surgery, which could help people with movement difficulties like those from stroke or cerebral palsy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-11135329 on NIH RePORTER

What this research studies

Many conditions, such as stroke or cerebral palsy, can make it hard to move because of changes in muscle strength and stiffness. Currently, it's difficult to accurately measure these muscle properties without invasive procedures. This project is working on a new approach using a special type of ultrasound, called shear wave elastography, to measure both muscle stiffness and force. By improving how we measure these factors, doctors could better understand how muscles work and create more effective rehabilitation plans.

Who could benefit from this research

Good fit: Patients experiencing movement difficulties due to conditions like stroke, cerebral palsy, or musculoskeletal injuries could potentially benefit from the future application of this research.

Not a fit: Individuals without movement disorders or muscle function changes would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this new measurement technique could lead to more personalized and effective rehabilitation treatments for various movement disorders.

How similar studies have performed: While ultrasound shear wave elastography has been explored before, this project proposes a novel interpretation to simultaneously measure both muscle stiffness and force, building on previous findings.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.