Understanding muscle loss in men with prostate cancer receiving hormone therapy
SArcopenia in Men with Prostate Cancer undergoing ADT (SAP-ADT)
This study is looking at how losing muscle mass and strength affects men with advanced prostate cancer who are receiving hormone therapy, and it aims to find ways to better support these patients over the next year.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Inst for Biomedical/clinical Res NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11010810 on NIH RePORTER |
What this research studies
This research investigates the loss of muscle mass and function, known as sarcopenia, in men diagnosed with advanced prostate cancer who are undergoing androgen deprivation therapy (ADT). The study aims to identify clinical outcomes and predictors of sarcopenia, as well as the biological mechanisms involved, particularly focusing on mitochondrial function. Participants will be monitored over a 12-month period to assess changes in body composition and muscle strength, which could help improve treatment strategies for these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with advanced prostate cancer who are about to start androgen deprivation therapy.
Not a fit: Patients with prostate cancer who are not undergoing androgen deprivation therapy or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management of sarcopenia in prostate cancer patients, improving their quality of life and treatment outcomes.
How similar studies have performed: Previous research has shown that addressing sarcopenia in cancer patients can lead to improved outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
Seattle, United States
- Seattle Inst for Biomedical/clinical Res — Seattle, United States (Active)
Researchers
- Principal investigator: Garcia, Jose M. — Seattle Inst for Biomedical/clinical Res
- Study coordinator: Garcia, Jose M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.