Understanding motor neuron types from development to adulthood
Defining Motor Neuron Diversity from Embryo to Adulthood and Generating Tools for in Vivo and in Vitro Access
This study is looking at the different kinds of motor neurons that help us move, from when they first form in embryos to when they are fully developed in adults, to better understand diseases like ALS and find new ways to study and treat them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-11085966 on NIH RePORTER |
What this research studies
This research investigates the diversity of motor neurons, which are crucial for body movement, from their formation in embryos to their mature state in adults. The team aims to identify different types of motor neurons and develop models that accurately reflect their functions and diseases like Amyotrophic Lateral Sclerosis (ALS). By mapping the changes in these neurons over time, the research seeks to create tools for better studying and manipulating these cells in laboratory settings. This could lead to improved understanding and treatment of conditions that affect motor neuron health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with motor neuron diseases such as Amyotrophic Lateral Sclerosis (ALS) or those at risk of developing such conditions.
Not a fit: Patients with non-neurological conditions or those who do not have motor neuron diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic and therapeutic strategies for patients with motor neuron diseases.
How similar studies have performed: Previous research has shown promise in understanding motor neuron diversity, but this approach aims to fill significant gaps in knowledge regarding adult motor neurons, making it a novel endeavor.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Patel, Tulsi — Rutgers Biomedical and Health Sciences
- Study coordinator: Patel, Tulsi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.