NIH-funded research NIH-funded research

Understanding mild cognitive impairment and Alzheimer's disease risk factors across different countries

Official title: Mild Cognitive Impairment and Alzheimer's Disease and Related Dementias: Cross-national longitudinal prognosis and risk factors

Funded at Columbia University Health Sciences · NIH-10940117 · Data updated 2026-11-12

This study is looking to find out how to spot people who might be at risk for Alzheimer's and related memory issues early on, especially those with mild cognitive impairment, so we can better understand how it develops and help create ways to prevent it, particularly in different communities around the world.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 22, 2024
Project endAugust 31, 2027
Funding year2024
Award (this year)$2,288,528
NIH project number1RF1AG088009-01
Project IDNIH-10940117 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adults over 21 years old who may be experiencing mild cognitive impairment or are at risk for Alzheimer's disease.

Less likely to help

Patients who do not have any cognitive impairment or are not at risk for Alzheimer's disease may not benefit from this research.

What this research studies

This research investigates the early identification of individuals at high risk for Alzheimer's disease and related dementias (ADRD), particularly focusing on mild cognitive impairment (MCI). It aims to improve the measurement of MCI and understand its progression in diverse populations, especially in low- and middle-income countries. By examining various social, economic, and cultural factors, the study seeks to identify key risk factors and develop better prevention strategies. Patients may be assessed through cognitive tests and evaluations to determine their risk levels.

Why it matters

Potential benefit: If successful, this research could lead to improved early detection and intervention strategies for Alzheimer's disease, potentially delaying its onset and progression.

How similar studies have gone: Previous research has shown success in identifying risk factors for Alzheimer's disease, but this study aims to expand understanding in underrepresented populations, making it a novel approach.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Arce, Miguel — Columbia University Health Sciences
  • Study coordinator: Arce, Miguel

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.