Understanding metabolism in diabetes and obesity using mouse models
Phenotyping Core
This study is helping scientists learn more about how diabetes and obesity affect our metabolism by using special mouse models, so they can find better ways to treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11016922 on NIH RePORTER |
What this research studies
This research focuses on providing advanced metabolic phenotyping services to scientists studying diabetes and obesity. By utilizing genetically manipulated mouse models, the project aims to measure key metabolic parameters and intracellular metabolic processes using cutting-edge techniques like stable and radio-labeled isotope methodology. The goal is to empower researchers with the tools needed to better understand the metabolic dysfunctions associated with these conditions, ultimately leading to new therapeutic strategies. The findings from this research could enhance our understanding of how diabetes and obesity affect metabolism.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research are individuals affected by diabetes or obesity, particularly those interested in the underlying metabolic mechanisms.
Not a fit: Patients who do not have diabetes or obesity, or those not involved in research studies, may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for diabetes and obesity by improving our understanding of their metabolic impacts.
How similar studies have performed: Other research has shown success with similar metabolic phenotyping approaches, indicating a promising avenue for understanding metabolic diseases.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Shulman, Gerald I — Yale University
- Study coordinator: Shulman, Gerald I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.