Understanding metabolism in diabetes and obesity using mouse models
Official title: Phenotyping Core
Funded at Yale University · NIH-11016922 · Data updated 2026-11-12
This study is helping scientists learn more about how diabetes and obesity affect our metabolism by using special mouse models, so they can find better ways to treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $228,877 |
| NIH project number | 5U2CDK134901-03 |
| Project ID | NIH-11016922 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research are individuals affected by diabetes or obesity, particularly those interested in the underlying metabolic mechanisms.
✕Less likely to help
Patients who do not have diabetes or obesity, or those not involved in research studies, may not receive direct benefits from this research.
What this research studies
This research focuses on providing advanced metabolic phenotyping services to scientists studying diabetes and obesity. By utilizing genetically manipulated mouse models, the project aims to measure key metabolic parameters and intracellular metabolic processes using cutting-edge techniques like stable and radio-labeled isotope methodology. The goal is to empower researchers with the tools needed to better understand the metabolic dysfunctions associated with these conditions, ultimately leading to new therapeutic strategies. The findings from this research could enhance our understanding of how diabetes and obesity affect metabolism.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for diabetes and obesity by improving our understanding of their metabolic impacts.
How similar studies have gone: Other research has shown success with similar metabolic phenotyping approaches, indicating a promising avenue for understanding metabolic diseases.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Shulman, Gerald I — Yale University
- Study coordinator: Shulman, Gerald I
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.