Understanding metabolic syndrome in tuberculosis patients in Tanzania
Official title: Metabolic Syndrome Outcomes Among Patients with Tuberculosis in Tanzania
Funded at Medical University of South Carolina · NIH-11033690 · Data updated 2026-11-12
This study is looking at how tuberculosis (TB) affects people’s metabolism, especially those who are newly diagnosed with TB and have pre-diabetes, to see how their health changes during treatment and what that means for their overall well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | December 10, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $201,549 |
| NIH project number | 1K23AI187709-01 |
| Project ID | NIH-11033690 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who have recently been diagnosed with tuberculosis and may also have pre-diabetes.
✕Less likely to help
Patients who do not have tuberculosis or metabolic syndrome may not receive any benefit from this research.
What this research studies
This research investigates the relationship between tuberculosis (TB) and metabolic syndrome, particularly focusing on how metabolic parameters change during TB treatment. It aims to analyze blood-based and physical markers in adults newly diagnosed with TB, especially those with pre-diabetes, to understand the severity of TB and its metabolic implications. By leveraging an ongoing cohort study in Tanzania, the research will provide insights into the dynamic health state of these patients and identify risk factors for various metabolic outcomes post-treatment.
Why it matters
Potential benefit: If successful, this research could lead to improved management strategies for patients with both TB and metabolic syndrome, enhancing their overall health outcomes.
How similar studies have gone: Previous research has shown significant interactions between diabetes and tuberculosis, indicating that this approach could yield valuable insights, although the specific intersection of TB and metabolic syndrome is less explored.
Where this research is happening
-
Medical University of South Carolina
Charleston, United States Active
Researchers
- Principal investigator: Alkabab, Yosra — Medical University of South Carolina
- Study coordinator: Alkabab, Yosra
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.