Understanding metabolic health changes during puberty

Metabolic Health during Puberty: the Healthy Start Study

NIH-funded research University of Colorado Denver · NIH-10878968

This study is looking at how puberty affects metabolic health and insulin levels in kids, especially those with Type 2 Diabetes, to better understand how their health changes during this important time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-10878968 on NIH RePORTER

What this research studies

This research investigates how metabolic health and insulin regulation change during puberty, particularly focusing on youth-onset Type 2 Diabetes (T2D). It aims to fill gaps in knowledge about the physiological changes that occur during this critical developmental period and how prior metabolic health influences these changes. By following a cohort of children from pregnancy through puberty, the study will collect data on various risk factors and their impact on metabolic health. This longitudinal approach will help identify patterns and predictors of T2D in youth.

Who could benefit from this research

Good fit: Ideal candidates for participation include children aged 0-21 years, particularly those with risk factors for obesity and Type 2 Diabetes.

Not a fit: Patients who are not within the age range of 0-21 years or do not have risk factors for Type 2 Diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for predicting and preventing Type 2 Diabetes in children and adolescents.

How similar studies have performed: Previous research has shown success in understanding metabolic health through longitudinal studies, but this specific focus on puberty and youth-onset T2D is relatively novel.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.