Understanding metabolic health and lifestyle impacts in individuals with Down syndrome
Metabolic Health, Lifestyle, and Risk of Co-Occurring Health Conditions in Down Syndrome (MET-DS)
This study is looking at how things like diet and exercise affect the health of young people with Down syndrome, and it will follow 200 participants aged 6 to 24 over five years to see how these factors might lead to other health issues.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11000652 on NIH RePORTER |
What this research studies
This research investigates how metabolic health and lifestyle factors contribute to the risk of developing additional health conditions in individuals with Down syndrome. It will follow 200 participants aged 6 to 24 years over five years, collecting detailed data on their metabolic health, lifestyle habits, and any co-occurring health issues. The study aims to uncover the complex relationships between these factors, which may help improve health outcomes for this population. Participants will be assessed annually through a rigorous deep-phenotyping protocol.
Who could benefit from this research
Good fit: Ideal candidates for this research are children, adolescents, and young adults aged 6 to 24 years who have been diagnosed with Down syndrome.
Not a fit: Patients outside the age range of 6 to 24 years or those without a diagnosis of Down syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health management strategies and interventions for individuals with Down syndrome, potentially reducing the prevalence of obesity and related health conditions.
How similar studies have performed: While there has been research on metabolic health in the general population, this specific focus on Down syndrome and its unique metabolic challenges is relatively novel.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Hartley, Sigan L — University of Wisconsin-Madison
- Study coordinator: Hartley, Sigan L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.