Understanding Memory Changes as We Age
Neurobehavioral Relations in Senescent Hippocampus
['FUNDING_R01'] · UNIVERSITY OF ARIZONA · NIH-11132819
This work aims to uncover why our memory changes as we get older, focusing on how brain circuits involved in memory are affected.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-11132819 on ClinicalTrials.gov |
What this research studies
As we age, many of us notice changes in our memory, especially with things like remembering where we put our keys or navigating new places. This research explores these natural memory changes by looking closely at how brain areas important for memory, like the hippocampus, function differently in older age. Scientists are using advanced techniques with animal models, including rats and nonhuman primates, to observe these brain changes at a very detailed level. The insights gained from these studies will help us understand the fundamental reasons behind age-related memory decline and could guide future work with people.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but focuses on understanding age-related memory changes relevant to anyone experiencing or concerned about cognitive decline.
Not a fit: Patients seeking immediate treatment or direct clinical intervention for memory issues would not directly benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of age-related memory decline, potentially informing strategies to maintain cognitive health as we age.
How similar studies have performed: Research into age-related cognitive changes is an active field, and this work builds upon existing knowledge while employing novel approaches to study brain circuits.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BARNES, CAROL A. — UNIVERSITY OF ARIZONA
- Study coordinator: BARNES, CAROL A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.