Understanding Memory Changes as We Age

Neural Selectivity, Retrieval-Related Reinstatement, and Age-Related MemoryDecline

['FUNDING_R01'] · UNIVERSITY OF TEXAS DALLAS · NIH-11111440

This research explores how our brains change as we get older, affecting our memory.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS DALLAS (nih funded)
Locations1 site (RICHARDSON, UNITED STATES)
Trial IDNIH-11111440 on ClinicalTrials.gov

What this research studies

As we get older, our memory often changes, especially for remembering specific events. Even small memory changes can affect our daily lives and overall well-being. This project aims to understand the specific brain processes that contribute to these age-related memory changes. Researchers are looking at how brain activity during memory formation and recall might differ in older adults compared to younger adults. By understanding these differences, we hope to find ways to help maintain memory as we age.

Who could benefit from this research

Good fit: Ideal candidates are healthy older adults experiencing typical age-related memory changes, particularly those in their 70s.

Not a fit: Patients with severe memory impairments or neurodegenerative diseases like Alzheimer's might not directly benefit from this foundational research.

Why it matters

Potential benefit: If successful, this research could lead to new ways to help people keep their memory sharp as they get older.

How similar studies have performed: Previous findings suggest that certain brain activities related to memory are weaker in older adults, providing a foundation for this deeper exploration.

Where this research is happening

RICHARDSON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.