Understanding Memory Changes and Alzheimer's Risk in Older African Americans

Risk Factors for Future Cognitive Decline and Alzheimers Disease in Older African Americans

NIH-funded research Rutgers the State Univ of Nj Newark · NIH-11091600

This project looks at why Alzheimer's disease is more common in older African Americans by exploring how health, lifestyle, environment, and genes affect brain health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers the State Univ of Nj Newark NIH-funded
Lab location1 site (Newark, United States)
Project IDNIH-11091600 on NIH RePORTER

What this research studies

Alzheimer's disease affects older African Americans at a higher rate, and we want to understand why this health difference exists. Our past work suggests that things like aerobic fitness and sleep quality play a role in memory decline and Alzheimer's. However, we also know that genetics and social factors can change how these lifestyle habits affect brain health. To learn more, we are inviting older African Americans to participate in follow-up visits to help us uncover these complex connections.

Who could benefit from this research

Good fit: Ideal candidates are cognitively healthy African Americans aged 60 and above, particularly those aged 80 and above for annual testing, living in the greater Newark, NJ area.

Not a fit: Patients who do not fit the age or ethnic criteria, or who are already experiencing significant cognitive decline, may not directly benefit from participating in this specific observational study.

Why it matters

Potential benefit: This work could lead to better ways to prevent or slow down Alzheimer's disease by identifying specific risk factors and understanding how they interact in older African Americans.

How similar studies have performed: Previous research has identified some health and lifestyle factors related to cognitive decline, and this project builds upon those findings by focusing specifically on older African Americans and complex interactions.

Where this research is happening

Newark, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.