Understanding memory and thinking changes in older breast cancer survivors
Official title: Cognitive aging in long-term breast cancer survivors
Funded at Sloan-Kettering Inst Can Research · NIH-11143046 · Data updated 2026-11-12
This work looks at how memory and thinking skills change over many years in older breast cancer survivors compared to people who haven't had cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $731,063 |
| NIH project number | 5R01CA276265-03 |
| Project ID | NIH-11143046 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this type of work would be breast cancer survivors diagnosed between ages 55 and 60, or non-cancer controls, within specific older age ranges.
✕Less likely to help
Patients who are not breast cancer survivors or who do not fall within the specified age ranges may not directly benefit from this particular research.
What this research studies
We want to understand how breast cancer and its treatments might affect your memory and thinking abilities many years later, especially as you get older. This project will compare the thinking skills of breast cancer survivors, diagnosed between ages 55 and 60, with people who have not had cancer. We will gather information from participants in three different age groups (65-69, 70-74, and 75-80) using online tests. This helps us see how these skills change over time and if factors like overall health and other medical conditions play a role.
Why it matters
Potential benefit: If successful, this work could help us better understand and predict long-term cognitive changes in breast cancer survivors, potentially leading to improved support and care strategies.
How similar studies have gone: Previous work has advanced our understanding of short-term cognitive effects after cancer treatment, but this work specifically addresses longer-term outcomes over many years, which is less understood.
Where this research is happening
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Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Root, James C — Sloan-Kettering Inst Can Research
- Study coordinator: Root, James C
Related research
Other NIH-funded projects on the same topics.
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Cognitive aging in long-term breast cancer survivors
This research explores how aging affects thinking and memory in people who survived breast cancer many years after treatment, focusing on those 65 and older.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.