Understanding malaria transmission and control in Ghana
Temporal strain structure and response to interventions in a high endemicity region of Plasmodium falciparum
['FUNDING_R01'] · NEW YORK UNIVERSITY · NIH-10985985
This study is looking at how the malaria parasite spreads in places like Ghana, especially among people who don’t feel sick but can still pass it on, to help find better ways to control and eliminate malaria.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10985985 on ClinicalTrials.gov |
What this research studies
This research investigates how the malaria parasite, Plasmodium falciparum, behaves in high transmission areas of sub-Saharan Africa, particularly in Ghana. It focuses on the asymptomatic carriers of the parasite, who do not show symptoms but can still spread the disease. By combining fieldwork and laboratory analysis, the study aims to understand the genetic diversity of the parasite and how it responds to different malaria control interventions, such as indoor spraying and seasonal medication. The research will track changes in the parasite population over time to improve strategies for malaria elimination.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in high malaria transmission areas of Ghana, particularly those who may be asymptomatic carriers of the parasite.
Not a fit: Patients living outside of high endemic malaria regions or those who are symptomatic and already receiving treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective malaria control strategies, reducing transmission and improving health outcomes in endemic regions.
How similar studies have performed: Previous research has shown that understanding the genetic diversity of malaria parasites can significantly enhance control measures, indicating that this approach has potential for success.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PASCUAL, MERCEDES — NEW YORK UNIVERSITY
- Study coordinator: PASCUAL, MERCEDES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.