Understanding Lymphatic Vessel Growth in Adult Lungs
Biology of Lymphangiogenesis in the Adult Lung
['FUNDING_R01'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-11141099
This project explores how the lymphatic system in adult lungs develops and repairs itself, which is important for keeping lungs healthy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY MEDICAL CAMPUS (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11141099 on ClinicalTrials.gov |
What this research studies
Our lungs have a special drainage system called the lymphatic system, which is vital for keeping them healthy by managing fluids and moving immune cells around. We don't fully understand how these lymphatic vessels grow and repair themselves in adults, or if there are different types of lymphatic cells with unique jobs, especially when fighting off infections. This project aims to uncover the basic biology of these lymphatic cells, including where they come from and how they multiply, particularly in response to challenges like an infection. By learning more about these cells, we hope to better understand how the lung's immune system works and how it recovers.
Who could benefit from this research
Good fit: This foundational research is not currently recruiting patients, but it focuses on understanding lung biology relevant to all adults.
Not a fit: Patients seeking immediate treatment options or direct clinical intervention will not find direct benefit from this basic science project.
Why it matters
Potential benefit: Understanding the basic biology of lung lymphatics could eventually lead to new treatments for lung diseases by improving how we manage fluid and immune responses.
How similar studies have performed: This project addresses significant knowledge gaps in the basic biology of the adult lung lymphatic system, making its approach novel and foundational.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY MEDICAL CAMPUS — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JONES, MATTHEW ROBERT — BOSTON UNIVERSITY MEDICAL CAMPUS
- Study coordinator: JONES, MATTHEW ROBERT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.