Understanding lung vulnerability and injury in patients with IPF
Official title: Human Tissue and Cell Core
Funded at University of Colorado Denver · NIH-10815860 · Data updated 2026-11-12
This study is looking at how a protein called MUC5B affects lung health in people with idiopathic pulmonary fibrosis (IPF) by collecting and analyzing lung tissue and cells from patients to learn more about their condition and improve future treatments.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $203,901 |
| NIH project number | 5P01HL162607-02 |
| Project ID | NIH-10815860 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis (IPF) and healthy controls.
✕Less likely to help
Patients with lung conditions other than IPF or those without any lung disease may not benefit from this research.
What this research studies
This research focuses on the role of a specific protein, MUC5B, in making lungs more susceptible to injury, particularly in patients with idiopathic pulmonary fibrosis (IPF). The Human Tissue and Cell Core will collect and analyze lung tissue and cells from IPF patients to better understand their condition. By recruiting participants and carefully phenotyping their clinical and radiologic features, the research aims to gather high-quality samples that can be used for various investigations related to lung health. This centralized resource will help in isolating and storing different types of lung cells for further study.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with idiopathic pulmonary fibrosis.
How similar studies have gone: Previous research has shown promise in using human tissue and cell samples to advance understanding of lung diseases, making this approach both relevant and potentially impactful.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Yang, Ivana V — University of Colorado Denver
- Study coordinator: Yang, Ivana V
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.