Understanding Lung Problems in People with HIV
HIV-Associated Lung Disease: The Role of Nasal Mucosal Immunity and Microbiome
This research explores how the nose's immune system and tiny organisms might contribute to lung problems in people living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11166544 on NIH RePORTER |
What this research studies
People living with HIV often face a higher risk of chronic lung diseases, and this research aims to understand why. We are looking closely at the immune factors and the community of microbes found in the nasal passages. By comparing these factors in people with HIV to those without, we hope to uncover how changes in the nose's environment might lead to lung issues. This work involves tracking these changes over time to see how they vary and what they mean for lung health.
Who could benefit from this research
Good fit: This research is relevant for people living with HIV who experience or are at risk for chronic lung diseases, as well as healthy individuals for comparison.
Not a fit: Patients whose lung conditions are unrelated to HIV infection or nasal immunity may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to predict, prevent, or treat lung diseases in people living with HIV.
How similar studies have performed: While the link between HIV and lung disease is known, this specific focus on nasal mucosal immunity and the microbiome as a mechanism is a novel approach.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Drummond, Michael Bradley — Univ of North Carolina Chapel Hill
- Study coordinator: Drummond, Michael Bradley
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.