Understanding lung injury from World Trade Center exposure through metabolic profiling and dietary changes
Metabolomics of World Trade Center-Lung Injury: Biomarker Validation, Longitudinal Assessment and Dietary Intervention
This study is looking at how dust from the World Trade Center might affect lung health and whether changing your diet can help, so we can find better ways to spot and treat lung problems for those who were exposed.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10848179 on NIH RePORTER |
What this research studies
This research investigates how exposure to particulate matter from the World Trade Center affects lung health by analyzing metabolic biomarkers and other biological factors. It aims to identify specific biosignatures that can predict lung injury and assess how dietary interventions can mitigate these effects. By using a multiOMIC approach, which includes studying metabolites, microbiomes, and genetic profiles, the research seeks to improve early diagnosis and treatment responses for affected individuals. The study will also evaluate the impact of nutritional changes on overall health and lung function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been exposed to World Trade Center particulate matter and are experiencing symptoms related to lung injury.
Not a fit: Patients who have not been exposed to World Trade Center particulate matter or do not exhibit any lung injury symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for individuals suffering from lung injuries related to environmental exposures.
How similar studies have performed: Previous research has shown promise in using metabolomic profiling for understanding lung injuries and other environmental health impacts, indicating that this approach could yield valuable insights.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Nolan, Anna — New York University School of Medicine
- Study coordinator: Nolan, Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.