Understanding lung health and disease progression
Deep Functional Phenotyping of the ALA Lung Health Cohort
This study is looking for healthy people across the U.S. to help us understand how lung health changes over time and what factors, like the environment and body traits, might lead to chronic respiratory diseases like asthma and COPD.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Vermont & St Agric College NIH-funded |
| Lab location | 1 site (Burlington, United States) |
| Project ID | NIH-10896464 on NIH RePORTER |
What this research studies
This research investigates how individuals transition from healthy lung function to chronic respiratory diseases. It involves recruiting healthy participants across the U.S. to evaluate their lung health through questionnaires, biospecimen analysis, spirometry, and CT imaging. The study aims to identify how various factors, including environmental influences and body characteristics, affect lung health. By focusing on a phenomenon called 'dysanapsis,' the research seeks to understand its role in conditions like asthma and COPD.
Who could benefit from this research
Good fit: Ideal candidates for this research are healthy individuals of all ages, particularly those interested in understanding their lung health.
Not a fit: Patients with existing chronic respiratory diseases may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for chronic lung diseases.
How similar studies have performed: Other research has shown promise in understanding lung health through similar methodologies, but this specific approach to dysanapsis is relatively novel.
Where this research is happening
Burlington, United States
- University of Vermont & St Agric College — Burlington, United States (Active)
Researchers
- Principal investigator: Irvin, Charles G — University of Vermont & St Agric College
- Study coordinator: Irvin, Charles G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.