Understanding Lung Disease in World Trade Center Workers
Chronic Obstructive Pulmonary Disase in WTC Workers - Diagnoses and Transitions
This project aims to better understand lung diseases, especially COPD, in World Trade Center workers and volunteers.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11075761 on NIH RePORTER |
What this research studies
We are looking closely at the different types of chronic lung diseases that affect World Trade Center workers and volunteers. Our goal is to find out what causes these conditions, what other health issues might be linked, and how lung function changes over time for these individuals. We will use advanced imaging techniques, like CT scans, to identify specific patterns of lung injury and track how the disease progresses. This work will help us understand why some people develop severe lung problems and others do not, leading to a better understanding of the disease process.
Who could benefit from this research
Good fit: Ideal candidates for this research are former World Trade Center workers and volunteers who are part of the existing occupational cohort at Mount Sinai.
Not a fit: Patients who are not WTC workers or volunteers, or who are not part of the Mount Sinai cohort, would not directly benefit from participation in this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more personalized treatments, better ways to monitor lung health, and improved strategies to prevent lung disease in WTC workers.
How similar studies have performed: While the specific focus on WTC-related COPD transitions and advanced imaging is unique, previous studies have characterized WTC-related health conditions and used imaging to understand lung injury.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: De la Hoz, Rafael E. — Icahn School of Medicine at Mount Sinai
- Study coordinator: De la Hoz, Rafael E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.