Understanding lung disease in cystic fibrosis using advanced imaging and blood tests
Imaging and Molecular Phenotyping of Cystic Fibrosis Lung Disease
This study is looking for better ways to spot early lung problems in people with cystic fibrosis by using new imaging techniques and blood tests, which could help doctors take action sooner to keep your lungs healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11009065 on NIH RePORTER |
What this research studies
This research focuses on improving the detection of early lung disease in cystic fibrosis (CF) patients by using advanced imaging techniques and blood tests. It aims to validate new proteomic biomarkers that can predict lung function decline and structural changes before traditional lung function tests show any issues. By analyzing blood serum and bronchoalveolar lavage fluid from CF patients, the study seeks to identify early signs of disease progression. This approach could lead to earlier interventions and better management of CF.
Who could benefit from this research
Good fit: Ideal candidates for this research include cystic fibrosis patients of all ages, particularly those who may be in the early stages of lung disease.
Not a fit: Patients with advanced cystic fibrosis lung disease who have already experienced significant lung function decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable earlier detection and treatment of lung disease in cystic fibrosis patients, potentially improving their long-term health outcomes.
How similar studies have performed: Previous research has shown promise in using advanced imaging and proteomic analysis for early disease detection, suggesting that this approach could be effective.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Cleveland, Zackary I — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Cleveland, Zackary I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.