Understanding lung development and diseases in infants and children
Research Center for Spatiotemporal Lung Imaging and Omics
This study is looking at how lungs grow and develop, especially in babies born early, to understand what helps them grow normally and what can cause lung problems, with the hope of finding better treatments for kids with chronic lung issues.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project ID | NIH-10681218 on NIH RePORTER |
What this research studies
This research focuses on the later stages of lung development, particularly the process of alveologenesis, which is crucial for lung maturation. By creating a molecular atlas of the developing lung, the project aims to uncover the mechanisms behind normal lung growth and the factors contributing to conditions like bronchopulmonary dysplasia in preterm infants. Utilizing advanced imaging techniques and cell-specific omics, the research will analyze lung development from birth through early adulthood, providing insights into both healthy and diseased lungs. Patients may benefit from the findings that could lead to improved treatments for chronic lung diseases in infants.
Who could benefit from this research
Good fit: Ideal candidates for this research include preterm infants and children with or at risk for bronchopulmonary dysplasia or other chronic lung conditions.
Not a fit: Patients with fully developed lungs or those without chronic lung diseases may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for chronic lung diseases in infants and children.
How similar studies have performed: Previous research has shown promise in understanding lung development and diseases, making this approach a continuation of successful methodologies.
Where this research is happening
Richland, United States
- Battelle Pacific Northwest Laboratories — Richland, United States (Active)
Researchers
- Principal investigator: Adkins, Joshua N. — Battelle Pacific Northwest Laboratories
- Study coordinator: Adkins, Joshua N.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.